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Neurol Clin. 2016 Feb;34(1):33-53. doi: 10.1016/j.ncl.2015.08.003.

Neurobehavioral Manifestations of Human Immunodeficiency Virus/AIDS: Diagnosis and Treatment.

Author information

1
NeuroInfectious Diseases Program, UCLA National Neurological AIDS Bank, David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Room A129, Los Angeles, CA 90095, USA. Electronic address: esinger@mednet.ucla.edu.
2
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, 740 Westwood Plaza, C8-746, Los Angeles, CA 90095, USA.

Abstract

Behavioral disorders are common in persons infected with human immunodeficiency virus (HIV). The differential includes preexisting psychiatric diseases, substance abuse, direct effects of HIV infection, opportunistic infection, and the adverse effects of medical therapies. Many patients have more than one contributing or comorbid problem to explain these behavioral changes. The differential should always include consideration of psychosocial, genetic, and medical causes of disease. Treatment strategies must take into account the coadministration of antiretroviral therapy and the specific neurologic problems common in patients infected with HIV.

KEYWORDS:

AIDS; Behavior; Brain; Delirium; Encephalitis; HIV; Infection

PMID:
26613994
PMCID:
PMC4663681
DOI:
10.1016/j.ncl.2015.08.003
[Indexed for MEDLINE]
Free PMC Article

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