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FEBS Lett. 1989 Jun 19;250(1):78-84.

Structures and functions associated with the group of mammalian lectins containing collagen-like sequences.

Author information

1
Institut for Medicinsk Microbiologi, J.B. Winsløwsvej 19, Odense C. Denmark.

Abstract

The number of proteins found in body fluids and at cell surfaces, which are known to display carbohydrate-binding properties, continues to increase rapidly. In these proteins, in addition to a domain associated with lectin properties, one or more, non-lectin domains are present. It is possible that binding of sugar residues by the lectin domain may be important in triggering a variety of recognition and clearance mechanisms via the non-lectin domains. The group of lectins containing collagen-like sequences may provide some insight into structure/function relationships of the different domains in view of the well defined structures already available for several of these molecules.

PMID:
2661270
DOI:
10.1016/0014-5793(89)80689-1
[Indexed for MEDLINE]
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