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J Mol Cell Cardiol. 2016 Jan;90:70-3. doi: 10.1016/j.yjmcc.2015.11.022. Epub 2015 Nov 22.

Not low hanging but still sweet: Metabolic proteomes in cardiovascular disease.

Author information

1
Department of Anesthesiology, David Geffen School of Medicine, UCLA, United States; Department of Medicine/Cardiology, David Geffen School of Medicine, UCLA, United States.
2
Department of Anesthesiology, David Geffen School of Medicine, UCLA, United States; Department of Medicine/Cardiology, David Geffen School of Medicine, UCLA, United States. Electronic address: tvondriska@mednet.ucla.edu.

Abstract

The application of proteomics in biology and medicine has reached a moment of truth. The demand of biologists for transformative insights into how cells work, plus the mandate of basic science research to ultimately impact clinical medicine, crystallize as a test on the rigor and reproducibility of any 'omics measurement. Studies like that by Boylston et al. indicate that proteomics can pass that test.

KEYWORDS:

Heart disease; Heart failure; Ischemia; Metabolism; Mitochondria; Myocardial; Proteomics; Systems biology

PMID:
26611885
DOI:
10.1016/j.yjmcc.2015.11.022
[Indexed for MEDLINE]

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