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Dev Cell. 2015 Nov 23;35(4):397-8. doi: 10.1016/j.devcel.2015.11.007.

ESCRT Filaments as Spiral Springs.

Author information

1
Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA.
2
Biophysics Graduate Program, University of California, Berkeley, Berkeley, CA 94720, USA.
3
Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA; Molecular Biophysics & Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: jimhurley@berkeley.edu.

Abstract

In a recent issue of Cell, Chiaruttini et al. (2015) reveal the mechanical properties of the mysterious spiral filaments formed by the yeast ESCRT-III protein Snf7. The spirals are shown to be springs whose bending drives membrane deformation and perhaps membrane scission.

PMID:
26609952
DOI:
10.1016/j.devcel.2015.11.007
[Indexed for MEDLINE]
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