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Transbound Emerg Dis. 2017 Jun;64(3):990-993. doi: 10.1111/tbed.12441. Epub 2015 Nov 25.

Isolation and Characterization of Madariaga Virus from a Horse in Paraíba State, Brazil.

Author information

1
Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Bolsista DCR/FAPEAM, Manaus, Brazil.
2
Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.
3
Departments of Pathology, and Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.
4
Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
5
Centro de Saúde e Tecnologia Rural, Universidade Federal de Campina Grande, Patos, Brazil.
6
Universidade Estadual Paulista, Botucatu, SP, Brazil.

Abstract

Madariaga virus (MADV), the new species designation for the South American isolates of eastern equine encephalitis virus (EEEV), is genetically divergent and substantially different in ecology and pathogenesis from North American EEEV strains. We isolated and characterized a MADV isolate obtained from a horse in Brazil. Our results support previous phylogenetic studies showing there are three genetically distinct MADV lineages. The MADV isolate from Paraíba State belongs to the South American lineage III and is closely related to Peruvian, Colombian and Venezuelan isolates.

KEYWORDS:

Alphavirus; Madariaga virus; arboviruses; eastern equine encephalitis virus; horse

PMID:
26608567
PMCID:
PMC4879107
DOI:
10.1111/tbed.12441
[Indexed for MEDLINE]
Free PMC Article

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