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Xenotransplantation. 2015 Nov-Dec;22(6):476-86. doi: 10.1111/xen.12208. Epub 2015 Nov 25.

The level of acceptance of spanish medical students of the transplantation of solid organs from animals: a stratified and multicentre study.

Author information

1
International Collaborative Donor Project ("Proyecto Colaborativo Internacional Donante"), Murcia, Spain.
2
Department of Surgery, Paediatrics, Obstetrics and Gynaecology, University of Murcia, Murcia, Spain.
3
Transplant Unit, Surgery Service, IMIB - Virgen de la Arrixaca University Hospital, Murcia, Spain.
4
Regional Transplant Centre, Consejería de Sanidad y Consumo de la Región de Murcia, Murcia, Spain.
5
Department of Psychology, Universidad Católica San Antonio (UCAM), Murcia, Spain.
6
Department of Urology, San Juan University Hospital of Alicante, Alicante, Spain.
7
Universidad de Granada, Granada, Spain.
8
Universidad de Navarra, Navarra, Spain.
9
Universidad Autónoma de Madrid, Madrid, Spain.
10
Servicio de Cirugía HBP y Trasplante Hepático, Complejo Hospitalario Universitario de Badajoz, Hospital Infanta Cristina, Badajoz, Spain.
11
Universidad de Cantabria, Santander, Spain.
12
Departamento de Cirugía, Ciencias Médicas y Sociales, Facultad de Medicina y Ciencias de la Salud, Universidad de Alcalá Campus Científico-Tecnológico, Alcala de Henares, Madrid, Spain.
13
Facultad de Medicina, Universidad de Málaga, Málaga, Spain.
14
Servicio de Urología (Complejo Hospitalario Universitario de Canarias, CHUC) y Departamento de Cirugía (Universidad de La Laguna, ULL) San Cristóbal de La Laguna, Tenerife, Spain.
15
Departamento de Ciencias Biomédicas Básicas, Facultad de Ciencias Biomédicas, Universidad Europea de Madrid, Madrid, Spain.
16
Universidad Rey Juan Carlos, Madrid, Spain.
17
Facultad de Medicina y Ciencias de la Salud, Área de Medicina Preventiva y Salud Pública, Universidad de Oviedo, Oviedo, Spain.
18
Departamento de Farmacología y Fisiología Facultad de Ciencias de la Salud y del Deporte, Universidad de Zaragoza, Huesca, Spain.
19
Universidad de las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
20
Universidad de Castilla La Mancha, Albacete, Spain.
21
Department of Immunology, Hospital del Mar, Barcelona, Spain.
22
Endocrinology and Nutrition Service, Unidad de Docencia y Formación Continuada, Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Servicio Murciano de Salud, El Palmar, Spain.
23
Hospital Regional de Alta Especialidad del Bajío, León, Mexico.
24
HGSZ No. 10 del Instituto Mexicano del Seguro Social Delegación Guanajuato, Guanajuato, Mexico.
25
Faculty of Veterinary, University of Murcia, Murcia, Spain.

Abstract

INTRODUCTION:

Research into the transplantation of solid organs from animals (xenotransplantation) is generating interest and curiosity given that this could be a way of resolving the shortage in transplant organs. However, the fact is that currently xenotransplantation is far from becoming a clinical practice.

OBJECTIVE:

To analyse the attitude of medical students from Spanish universities towards the donation of organs from animals and to determine the factors affecting their attitudes.

MATERIAL AND METHODS:

TYPE OF STUDY:

A sociological, interdisciplinary, observational and multicentre study in Spain.

STUDY POPULATION:

Students enrolled on the medical degree in Spain (n = 34 000).

SAMPLE SIZE:

A sample of 9598 students (a confidence level of 99% and precision of ± 1%) stratified by geographical area and academic year. Instrument of measurement: A validated questionnaire of attitude towards organ xenotransplantation (PCID-XenoTx RIOS) which was self-administered and completed anonymously.

RESULTS:

A completion rate of 95.7% (n = 9275) was obtained. If the results of xenotransplantation were as good as in human donation, 81% (n = 7491) would be in favour, 3% (n = 308) against and 16% (n = 1476) undecided. The following variables affected this attitude: sex (P < 0.001); academic year (P < 0.001); discussion of transplantation with one's family (P < 0.001) and friends (P < 0.001); the opinion of one's partner (P < 0.001); the respondent's attitude towards organ donation (P < 0.001); religion (P < 0.001); and participation in altruistic activities (P < 0.001). The following variables persisted in the multivariate analysis: (1) being a female (OR = 1.794; P < 0.001); (2) academic year (OR = 2.487; P < 0.001); (3) having spoken about the issue with one's family (OR = 1.200; P = 0.019); (4) the favourable opinion of one's partner (OR = 1.526; P = 0.028); (5) an attitude in favour of donation (OR = 2.087; P < 0.001); (6) being an atheist/agnostic, (OR = 2.5; P < 0.001); and (7) a belief that one's religion is in favour of transplantation (OR = 1.317; P = 0.005).

CONCLUSIONS:

Spanish medical students have a favourable attitude towards xenotransplantation. This willingness and interest could be a decisive platform for the development and strengthening of research, both for centres with a pre-clinical xenotransplantation programme and new healthcare centres.

KEYWORDS:

Spain; attitude; medical students; organ donation; psycho-social variables; transplant; university; xenotransplantation

PMID:
26602493
DOI:
10.1111/xen.12208
[Indexed for MEDLINE]

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