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Nat Commun. 2015 Nov 24;6:10033. doi: 10.1038/ncomms10033.

Gekko japonicus genome reveals evolution of adhesive toe pads and tail regeneration.

Author information

1
JS Key Laboratory of Neuroregeneration, Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226001, China.
2
Beijing Genomics Institute, BGI-Shenzhen, Shenzhen 518083, China.
3
Chengdu institute of biology, Chinese Academy of Sciences, Chengdu 610041, China.
4
James D. Watson Institute of Genome Sciences, Hangzhou 610041, China.

Abstract

Reptiles are the most morphologically and physiologically diverse tetrapods, and have undergone 300 million years of adaptive evolution. Within the reptilian tetrapods, geckos possess several interesting features, including the ability to regenerate autotomized tails and to climb on smooth surfaces. Here we sequence the genome of Gekko japonicus (Schlegel's Japanese Gecko) and investigate genetic elements related to its physiology. We obtain a draft G. japonicus genome sequence of 2.55 Gb and annotated 22,487 genes. Comparative genomic analysis reveals specific gene family expansions or reductions that are associated with the formation of adhesive setae, nocturnal vision and tail regeneration, as well as the diversification of olfactory sensation. The obtained genomic data provide robust genetic evidence of adaptive evolution in reptiles.

PMID:
26598231
PMCID:
PMC4673495
DOI:
10.1038/ncomms10033
[Indexed for MEDLINE]
Free PMC Article

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