Format

Send to

Choose Destination
Food Chem. 2016 Apr 1;196:493-502. doi: 10.1016/j.foodchem.2015.09.077. Epub 2015 Sep 25.

Evaluation of the nutraceutical, antioxidant and cytoprotective properties of ripe pistachio (Pistacia vera L., variety Bronte) hulls.

Author information

1
Dipartimento di Scienze Chimiche, Università di Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
2
Dipartimento di Scienze del Farmaco e dei Prodotti per la Salute, Università di Messina, Villaggio S.S. Annunziata, 98168 Messina, Italy.
3
Dipartimento di Scienze del Farmaco e dei Prodotti per la Salute, Università di Messina, Villaggio S.S. Annunziata, 98168 Messina, Italy. Electronic address: dtrombetta@unime.it.

Abstract

Every year tons of pistachio hulls are separated and eliminated, as waste products, from pistachio seeds. In this study the hulls of ripe pistachios were extracted with two organic solvents (ethanol and methanol) and characterized for phenolic composition, antioxidant power and cytoprotective activity. RP-HPLC-DAD-FLU separation enabled us to identify 20 derivatives, including and by far the most abundant gallic acid, 4-hydroxybenzoic acid, protocatechuic acid, naringin, eriodictyol-7-O-glucoside, isorhamnetin-7-O-glucoside, quercetin-3-O-rutinoside, isorhamnetin-3-O-glucoside and catechin. Methanol extraction gave the highest yields for all classes of compounds and presented a higher scavenging activity in all the antioxidant assays performed. The same was found for cytoprotective activity on lymphocytes, lipid peroxidation and protein degradation. These findings highlight the strong antioxidant and cytoprotective activity of the extract components, and illustrate how a waste product can be used as a source of nutraceuticals to employ in manufacturing industry.

KEYWORDS:

Antioxidant activity; Cytoprotective activity; FRAP; Lipid peroxidation; ORAC; Pistacia vera L., variety Bronte; RP-HPLC-DAD-FLU

PMID:
26593519
DOI:
10.1016/j.foodchem.2015.09.077
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center