Impact of Nutrition on Bronchopulmonary Dysplasia

Clin Perinatol. 2015 Dec;42(4):797-806. doi: 10.1016/j.clp.2015.08.007. Epub 2015 Oct 2.

Abstract

Bronchopulmonary dysplasia (BPD) remains a common morbidity of prematurity. Although the pathogenesis of BPD is recognized to be both multifactorial and complex, the role of nutrition in the pathophysiology of BPD is typically limited to management after a diagnosis has been made. Infants born small for gestational age and those who experience postnatal growth failure are more likely to have BPD. Therapies for lung disease, such as fluid restriction, diuretics, and corticosteroids, can negatively impact postnatal growth. Future research is needed to optimize nutritional strategies in the neonatal intensive care unit and following hospital discharge.

Keywords: Bronchopulmonary dysplasia; Growth; Nutrition; Premature infants.

Publication types

  • Review

MeSH terms

  • Bronchopulmonary Dysplasia* / physiopathology
  • Bronchopulmonary Dysplasia* / therapy
  • Child Development
  • Dietary Supplements
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Infant, Premature / growth & development*
  • Nutritional Status*
  • Parenteral Nutrition / methods*