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Nucleic Acids Res. 2016 Jan 4;44(D1):D717-25. doi: 10.1093/nar/gkv1275. Epub 2015 Nov 20.

The UCSC Genome Browser database: 2016 update.

Author information

1
Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA mspeir@soe.ucsc.edu.
2
Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.
3
Invitae, San Francisco, CA 94017, USA.
4
Institute for Human Genetics, University of California San Francisco, San Francisco, CA 94143, USA.
5
Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA Howard Hughes Medical Institute, University of California Santa Cruz, CA 95064, USA.

Abstract

For the past 15 years, the UCSC Genome Browser (http://genome.ucsc.edu/) has served the international research community by offering an integrated platform for viewing and analyzing information from a large database of genome assemblies and their associated annotations. The UCSC Genome Browser has been under continuous development since its inception with new data sets and software features added frequently. Some release highlights of this year include new and updated genome browsers for various assemblies, including bonobo and zebrafish; new gene annotation sets; improvements to track and assembly hub support; and a new interactive tool, the "Data Integrator", for intersecting data from multiple tracks. We have greatly expanded the data sets available on the most recent human assembly, hg38/GRCh38, to include updated gene prediction sets from GENCODE, more phenotype- and disease-associated variants from ClinVar and ClinGen, more genomic regulatory data, and a new multiple genome alignment.

PMID:
26590259
PMCID:
PMC4702902
DOI:
10.1093/nar/gkv1275
[Indexed for MEDLINE]
Free PMC Article

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