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Haematologica. 2016 Mar;101(3):e99-102. doi: 10.3324/haematol.2015.133470. Epub 2015 Nov 20.

Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative co-operativity of the receptors.

Author information

1
Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria Salzburg Cancer Research Institute, Austria.
2
Tyrolean Cancer Research Institute, Innsbruck, Austria.
3
Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), Division Medicinal Chemistry, VU University Amsterdam, the Netherlands.
4
Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico, Aviano, Italy.
5
Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria Salzburg Cancer Research Institute, Austria t.hartmann@salk.at.

KEYWORDS:

B-cell receptor; CLL; CXCL12; chemokine; microenvironment

PMID:
26589908
PMCID:
PMC4815737
DOI:
10.3324/haematol.2015.133470
[Indexed for MEDLINE]
Free PMC Article

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