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Eye (Lond). 2016 Mar;30(3):400-5. doi: 10.1038/eye.2015.242. Epub 2015 Nov 20.

Biometric and refractive changes after orbital decompression in Korean patients with thyroid-associated orbitopathy.

Author information

1
Department of Ophthalmology, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, Korea.
2
Thyroid Center, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, Korea.

Abstract

PURPOSE:

To determine the biometric and refractive changes after orbital decompression in Korean patients with thyroid-associated orbitopathy (TAO).

METHODS:

Retrospective, observational study (between October 2012 and September 2014) was performed. Patients with TAO undergoing orbital decompression for stable proptosis received ophthalmic examinations, including Hertel exophthalmometry, A-scan biometry, autorefraction measures, corneal topography, and wavefront aberration measures, before orbital decompression and again 2 months after surgery.

RESULTS:

Included in the study were 43 eyes from 23 patients. The mean exophthalmometric value decreased by 4.1 mm 2 months after orbital decompression (P<0.001). On average, axial length (AL) increased significantly by 0.08 mm (P<0.001); specifically, 37 (86%) of the 43 eyes had increased AL. Whereas anterior chamber depth and lens thickness showed no significant changes (P=0.086 and P=0.905, respectively), the mean spherical refraction and spherical equivalent (SE) decreased by 0.35 and 0.48 D, respectively (P=0.008 and P<0.001, respectively). However, cylindrical refraction and axis showed no significant changes (P=0.057 and P=0.218, respectively). The changes in AL and SE were significantly correlated (R=-0.411, P=0.009). Notably, there were no changes in corneal topography or wavefront aberration after orbital decompression.

CONCLUSIONS:

TAO patients who underwent orbital decompression showed myopic refractive change via increase in AL. Possible refractive changes should be considered in cases of TAO complaining of decreased visual acuity after orbital decompression.

PMID:
26584795
PMCID:
PMC4791698
[Available on 2017-03-01]
DOI:
10.1038/eye.2015.242
[Indexed for MEDLINE]
Free PMC Article

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