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Nucleic Acids Res. 2016 Jan 4;44(D1):D774-80. doi: 10.1093/nar/gkv1217. Epub 2015 Nov 17.

WormBase 2016: expanding to enable helminth genomic research.

Author information

  • 1European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK kevin.howe@wormbase.org.
  • 2European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
  • 3Informatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada.
  • 4Division of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
  • 5Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • 6Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • 7Informatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA.

Abstract

WormBase (www.wormbase.org) is a central repository for research data on the biology, genetics and genomics of Caenorhabditis elegans and other nematodes. The project has evolved from its original remit to collect and integrate all data for a single species, and now extends to numerous nematodes, ranging from evolutionary comparators of C. elegans to parasitic species that threaten plant, animal and human health. Research activity using C. elegans as a model system is as vibrant as ever, and we have created new tools for community curation in response to the ever-increasing volume and complexity of data. To better allow users to navigate their way through these data, we have made a number of improvements to our main website, including new tools for browsing genomic features and ontology annotations. Finally, we have developed a new portal for parasitic worm genomes. WormBase ParaSite (parasite.wormbase.org) contains all publicly available nematode and platyhelminth annotated genome sequences, and is designed specifically to support helminth genomic research.

PMID:
26578572
PMCID:
PMC4702863
DOI:
10.1093/nar/gkv1217
[PubMed - indexed for MEDLINE]
Free PMC Article
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