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Adv Protein Chem Struct Biol. 2015;101:213-29. doi: 10.1016/bs.apcsb.2015.08.003. Epub 2015 Sep 26.

Porous Alumina as a Promising Biomaterial for Public Health.

Author information

1
Department of Health Sciences (DISSAL), Via Antonio Pastore 1, University of Genoa, Genoa, Italy.
2
Department of Health Sciences (DISSAL), Via Antonio Pastore 1, University of Genoa, Genoa, Italy. Electronic address: robertobragazzi@gmail.com.
3
Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.

Abstract

Porous aluminum is a nanostructured material characterized by unique properties, such as chemical stability, regular uniformity, dense hexagonal porous lattice with high aspect ratio nanopores, excellent mechanical strength, and biocompatibility. This overview examines how the structure and properties of porous alumina can be exploited in the field of public health. Porous alumina can be employed for fabricating membranes and filters for bioremediation, water ultrafiltration, and microfiltration/nanofiltration, being a promising technique for having clean and fresh water, which is essential for human health. Porous alumina-based nanobiosensor coated with specific antibodies or peptides seem to be a useful tool to detect and remove pathogens both in food and in water, as well as for environmental monitoring. Further, these applications, being low-energy demanding and cost-effective, are particularly valuable in resource-limited settings and contexts, and can be employed as point of use devices in developing countries, where there is an urgent need of hygiene and safety assurance.

KEYWORDS:

Biomaterials for public health; Biosensors; Environmental monitoring; Food hygiene; Label-free devices; Nanobiotechnologies for public health; Pathogen detection; Public health; Water hygiene

PMID:
26572980
DOI:
10.1016/bs.apcsb.2015.08.003
[Indexed for MEDLINE]

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