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Nature. 2015 Dec 3;528(7580):84-7. doi: 10.1038/nature15736. Epub 2015 Nov 16.

Pharmacogenomic agreement between two cancer cell line data sets.

Abstract

Large cancer cell line collections broadly capture the genomic diversity of human cancers and provide valuable insight into anti-cancer drug response. Here we show substantial agreement and biological consilience between drug sensitivity measurements and their associated genomic predictors from two publicly available large-scale pharmacogenomics resources: The Cancer Cell Line Encyclopedia and the Genomics of Drug Sensitivity in Cancer databases.

PMID:
26570998
PMCID:
PMC6343827
DOI:
10.1038/nature15736
[Indexed for MEDLINE]
Free PMC Article

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