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Expert Rev Respir Med. 2016;10(1):69-77. doi: 10.1586/17476348.2016.1121104. Epub 2015 Dec 7.

Exercise training in idiopathic pulmonary fibrosis.

Author information

a Pulmonary Institute, Rabin Medical Center , Beilinson Hospital , Petach Tikva , Israel.
b Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport , University of Porto , Porto , Portugal.
c Sackler Faculty of Medicine , Tel Aviv University , Tel Aviv , Israel.


Idiopathic pulmonary fibrosis (IPF) is a chronic devastating interstitial lung disease associated with exercise intolerance, dyspnea, hypoxemia, diminished quality of life and poor prognosis. A growing body of evidence with respect to short-term effects of exercise training has demonstrated clinical benefits in IPF patients. A recent systematic review showed significant improvements in 6-min walking distance, peak aerobic capacity, reduced dyspnea and improved quality of life. However, aspects of training programs, maintenance and predictors of improvement and the impact on prognosis need to be further explored. The aim of this paper was to comprehensively review the existing scientific literature regarding exercise training in patients with IPF and identify important gaps that should be studied in the future.


6-min walking distance; Exercise tolerance; dyspnea; quality of life

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