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Clin Infect Dis. 2015 Dec 1;61 Suppl 6:S618-21. doi: 10.1093/cid/civ815.

The Role of Echinocandins in Candida Biofilm-Related Vascular Catheter Infections: In Vitro and In Vivo Model Systems.

Author information

1
Center for Medical Mycology, Department of Dermatology, Case Western Reserve University, Cleveland, Ohio.
2
Infectious Diseases Unit, Third Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Hippokration Hospital, Thessaloniki, Greece.
3
Transplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine.
4
Transplantation-Oncology Infectious Diseases Program, Division of Infectious Diseases, Department of Medicine Department of Pediatrics and Department of Microbiology and Immunology, Weill Cornell Medical Center of Cornell University, New York, New York.

Abstract

Candida biofilm-associated infections of central venous catheters are a challenging therapeutic problem. Recent in vitro and in vivo studies of the structure, formation, pathogenesis, and treatment establish a rationale for new approaches to management of these tenacious infections.

KEYWORDS:

anidulafungin; biofilm; caspofungin; echinocandin; micafungin

PMID:
26567279
DOI:
10.1093/cid/civ815
[Indexed for MEDLINE]

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