Format

Send to

Choose Destination
Am J Med Genet A. 2016 Feb;170A(2):363-374. doi: 10.1002/ajmg.a.37459. Epub 2015 Nov 14.

"This lifetime commitment": Public conceptions of disability and noninvasive prenatal genetic screening.

Author information

1
Stanford Center for Biomedical Ethics, Stanford, California.
2
Biomedical Ethics Research Program and Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota.
3
Institute for Health and Aging, University of California, San Francisco, California.

Abstract

Recently, new noninvasive prenatal genetic screening technologies for Down syndrome and other genetic conditions have become commercially available. Unique characteristics of these screening tests have reignited long-standing concerns about prenatal testing for intellectual and developmental disabilities. We conducted a web-based survey of a sample of the US public to examine how attitudes towards disability inform views of prenatal testing in the context of these rapidly advancing prenatal genetic screening technologies. Regardless of opinion toward disability, the majority of respondents supported both the availability of screening and the decision to continue a pregnancy positive for aneuploidy. Individuals rationalized their support with various conceptions of disability; complications of the expressivist argument and other concerns from the disability literature were manifested in many responses analyzed.

KEYWORDS:

NIPS; cell-free DNA; disability rights; down syndrome; intellectual disabilities; noninvasive prenatal screening; prenatal testing; public opinion; trisomy

PMID:
26566970
PMCID:
PMC4948186
DOI:
10.1002/ajmg.a.37459
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center