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Nephrol Ther. 2016 Feb;12(1):38-47. doi: 10.1016/j.nephro.2015.07.471. Epub 2015 Nov 10.

[Mineral-based alkaline waters' prescription in France: Patients are the key point for both nephrologists and urologists].

[Article in French]

Author information

1
Centre associatif lyonnais de dialyse (CALYDIAL), 51, rue Yvours, 69540 Irigny, France; Club des jeunes néphrologues, 11, rue Auguste-Mourcou, 59000 Lille, France.
2
Club des jeunes néphrologues, 11, rue Auguste-Mourcou, 59000 Lille, France; Service de néphrologie, centre hospitalier Alpes-Léman, 74130 Contamine-sur-Arve, France.
3
Club des jeunes néphrologues, 11, rue Auguste-Mourcou, 59000 Lille, France; Service de médecine interne et néphrologie, centre hospitalier de Valenciennes, avenue Desandrouin, 59300 Valenciennes, France.
4
Club des jeunes néphrologues, 11, rue Auguste-Mourcou, 59000 Lille, France; Institut phocéen de néphrologie, clinique Bouchard, 13006 Marseille, France.
5
Club des jeunes néphrologues, 11, rue Auguste-Mourcou, 59000 Lille, France; Service de néphrologie et transplantation rénale, CHRU La Cavale-Blanche, boulevard Tanguy-Prigent, 29609 Brest, France.
6
Club des jeunes néphrologues, 11, rue Auguste-Mourcou, 59000 Lille, France; Service de dialyse, HIA Sainte-Anne, boulevard Sainte-Anne, 83000 Toulon, France.
7
Service d'urologie, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France; Association française des urologues en formation, Maison de l'urologie, 11, rue Viète, 75017 Paris, France.
8
Association française des urologues en formation, Maison de l'urologie, 11, rue Viète, 75017 Paris, France; Service de chirurgie infantile, hôpital Mère-Enfant, 38, boulevard Jean-Monnet, 44093 Nantes, France.
9
Dauphine recherches en management, UMR CNRS 7088, université Paris Dauphine, place du Maréchal-de-Lattre-de-Tassigny, 75016 Paris, France.
10
Association française des urologues en formation, Maison de l'urologie, 11, rue Viète, 75017 Paris, France; Service d'urologie, CHU de Grenoble, laboratoire TIMC-IMAG, CNRS, université Grenoble-Alpes, 38000 Grenoble, France.
11
Club des jeunes néphrologues, 11, rue Auguste-Mourcou, 59000 Lille, France; Service d'explorations fonctionnelles rénales et métaboliques, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France. Electronic address: jean-philippe.bertocchio@aphp.fr.

Abstract

Alkali therapy is frequently used during chronic kidney disease and nephrolithiasis: nephrologists and urologists are the key operators. Very few is known about the underlying conditions of such a prescription: the aim of this study was to delineate those determinants. We conducted a prospective survey where French nephrologists and urologists were involved. Responders were without gender distinction and principally nephrologists. Prescription frequency was associated with gender (women), specialty (nephrologists), indications and perceived efficiency. Urologists prescribe more often during nephrolithiasis and nephrologists during chronic kidney disease. Urologists were more expert (by scoring on mineral-based alkaline waters compositions knowledge). By multivariate analysis, prescription frequency is associated with gender (women), indications and perceived efficiency by prescribers, which is itself influenced by feedback from patients. These results could have been influenced by a huge representation of nephrologists but foster physicians to go on listening to feedback from patients, due to a lack of clinical trials on the efficiency of mineral-based alkaline waters in such a field. Finally, physicians' education (especially young nephrologists) on mineral-based alkaline waters should be intensified.

KEYWORDS:

Acidose; Acidosis; Bicarbonates; Drug utilization review; Hydrogénocarbonates; Insuffisance rénale chronique; Nephrolithiasis; Néphrolithiase; Renal insufficiency chronic; Revue des pratiques de prescription des médicaments

PMID:
26563589
DOI:
10.1016/j.nephro.2015.07.471
[Indexed for MEDLINE]

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