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Nat Prod Rep. 2016 Jan;33(1):87-110. doi: 10.1039/c5np00102a.

Bacterial terpene cyclases.

Author information

1
University of Bonn, Kekulé-Institute of Organic Chemistry and Biochemistry, Gerhard-Domagk-Straße 1, 53121 Bonn, Germany. dickschat@uni-bonn.de.

Abstract

Covering: up to 2015. This review summarises the accumulated knowledge about characterised bacterial terpene cyclases. The structures of identified products and of crystallised enzymes are included, and the obtained insights into enzyme mechanisms are discussed. After a summary of mono-, sesqui- and diterpene cyclases the special cases of the geosmin and 2-methylisoborneol synthases that are both particularly widespread in bacteria will be presented. A total number of 63 enzymes that have been characterised so far is presented, with 132 cited references.

PMID:
26563452
DOI:
10.1039/c5np00102a
[Indexed for MEDLINE]

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