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Expert Rev Anti Infect Ther. 2015;13(12):1433-40. doi: 10.1586/14787210.2015.1116939. Epub 2015 Dec 2.

Once-daily luliconazole cream 1% for the treatment of interdigital tinea pedis.

Author information

1
a Valeant Pharmaceuticals North America LLC , Bridgewater , NJ , USA.

Abstract

Luliconazole is an imidazole antifungal agent with a unique chemical structure. In this article, we summarize the in vitro data, animal studies and clinical trial data relating to the use of topical luliconazole cream 1% in the treatment of tinea pedis. Preclinical studies have demonstrated potent activity against dermatophytes. Luliconazole has strong fungicidal activity against Trichophyton spp., similar to that seen with terbinafine. Evidence from clinical trials in tinea pedis have shown once-daily application of luliconazole cream 1% for 14 days to be effective and well tolerated.

KEYWORDS:

efficacy; interdigital tinea pedis; luliconazole; once-daily; safety; short-course therapy

PMID:
26559086
DOI:
10.1586/14787210.2015.1116939
[Indexed for MEDLINE]

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