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Z Geburtshilfe Neonatol. 2015 Oct;219(5):238-42. doi: 10.1055/s-0035-1555873. Epub 2015 Nov 10.

Late Vitamin K Deficient Bleeding in 2 Young Infants--Renaissance of a Preventable Disease.

Author information

1
University Children's Hospital, Wuerzburg, Wuerzburg, Germany.
2
Division of Pediatric Neurosurgery, Department of Neurosurgery, University of Wuerzburg, Wuerzburg, Germany.

Abstract

INTRODUCTION:

Late vitamin K deficiency bleeding in young infants is a rare disorder which occurs almost exclusively in breast-fed infants who did not receive proper vitamin K prophylaxis at birth and who might additionally suffer from cholestasis. Its impact on morbidity is high since in 50% of the cases it presents with intracranial hemorrhage with a mortality rate of 20% and life-long neurologic sequelae in 30% of the affected infants.

CASE REPORTS:

2 male infants were both admitted to our unit at the age of 5 weeks with subdural hematoma with midline shift due to late vitamin K deficiency bleeding. Both infants did not receive the recommended Vitamin K prophylaxis in Germany. One patient presented with cholestatic jaundice on admission as an additional risk factor.

DISCUSSION:

Parents who in the apparent best interest for their children refuse the recommended and well established vitamin K prophylaxis at birth leading to the reappearance of late vitamin K deficiency bleeding. These parents also tend to refuse routine immunizations of childhood in later life, which not only have an impact on their own child but might bear a risk for the whole community.

CONCLUSION:

It is the responsibility of health-care takers to show increased awareness to the growing number of parents refusing vitamin K prophylaxis at birth and educate them properly about the devastating consequences of late vitamin K deficiency bleeding.

PMID:
26556811
DOI:
10.1055/s-0035-1555873
[Indexed for MEDLINE]

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