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Amino Acids. 2016 Mar;48(3):779-789. doi: 10.1007/s00726-015-2125-8. Epub 2015 Nov 9.

Ten weeks of branched-chain amino acid supplementation improves select performance and immunological variables in trained cyclists.

Author information

1
School of Kinesiology, Molecular and Applied Sciences Laboratory, Auburn University, 301 Wire Road, Office 286, Auburn, AL, 36849, USA.
2
Wichita State University, Wichita, KS, USA.
3
Harrison School of Pharmacy, Auburn University, Auburn, AL, USA.
4
Edward Via College of Osteopathic Medicine, Auburn Campus, Auburn, AL, USA.
5
Endurance Company, LLC, Bloomington, IL, USA.
6
MusclePharm Sports Science Institute, Denver, CO, USA.
7
School of Kinesiology, Molecular and Applied Sciences Laboratory, Auburn University, 301 Wire Road, Office 286, Auburn, AL, 36849, USA. mdr0024@auburn.edu.
8
Edward Via College of Osteopathic Medicine, Auburn Campus, Auburn, AL, USA. mdr0024@auburn.edu.

Abstract

We examined if supplementing trained cyclists (32 ± 2 year, 77.8 ± 2.6 kg, and 7.4 ± 1.2 year training) with 12 g/day (6 g/day L-Leucine, 2 g/day L-Isoleucine and 4 g/day L-Valine) of either branched-chain amino acids (BCAAs, n = 9) or a maltodextrin placebo (PLA, n = 9) over a 10-week training season affected select body composition, performance, and/or immune variables. Before and after the 10-week study, the following was assessed: (1) 4-h fasting blood draws; (2) dual X-ray absorptiometry body composition; (3) Wingate peak power tests; and (4) 4 km time-trials. No group × time interactions existed for total lean mass (P = 0.27) or dual-leg lean mass (P = 0.96). A significant interaction existed for body mass-normalized relative peak power (19 % increase in the BCAA group pre- to post-study, P = 0.01), and relative mean power (4 % increase in the BCAA group pre- to post-study, P = 0.01). 4 km time-trial time to completion approached a significant interaction (P = 0.08), as the BCAA group improved in this measure by 11 % pre- to post-study, though this was not significant (P = 0.15). There was a tendency for the BCAA group to present a greater post-study serum BCAA: L-Tryptophan ratio compared to the PLA group (P = 0.08). A significant interaction for neutrophil number existed (P = 0.04), as there was a significant 18 % increase within the PLA group from the pre- to post-study time point (P = 0.01). Chronic BCAA supplementation improves sprint performance variables in endurance cyclists. Additionally, given that BCAA supplementation blunted the neutrophil response to intense cycling training, BCAAs may benefit immune function during a prolonged cycling season.

KEYWORDS:

Cycling; Immunity; Isoleucine; Leucine; Peak power; Valine

PMID:
26553453
DOI:
10.1007/s00726-015-2125-8
[Indexed for MEDLINE]

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