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J Knee Surg. 2016 Aug;29(6):502-9. doi: 10.1055/s-0035-1566736. Epub 2015 Nov 9.

Effect of Sodium Hyaluronate on Recovery after Arthroscopic Knee Surgery.

Author information

1
Department of Trauma and Orthopaedics, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.
2
Department of Trauma and Orthopaedics, University Hospital of North Tees, Stockton, United Kingdom.
3
Department of Trauma and Orthopaedics, Sarathi Superspeciality Orthopaedic Centre, Bangalore, India.
4
Department of Physiotherapy, The Royal Oldham Hospital, Oldham, United Kingdom.
5
Department of Trauma and Orthopaedics, The Royal Oldham Hospital, Oldham, United Kingdom.

Abstract

The aim of this study was to evaluate the effect of a single immediate postoperative instillation of 10 mL of sodium hyaluronate (Viscoseal) into the knee following arthroscopy. A single-center, prospective, randomized, controlled study was undertaken. Consenting knee arthroscopy patients were randomized into two groups following surgery: the study group received 10 mL of sodium hyaluronate intra-articularly, while the control group received an intra-articular instillation of 10 mL of Bupivacaine. Pre- and postoperative visual analogue scale scores for pain and Western Ontario and McMaster Universities (WOMAC) scores for knee function were obtained. Overall, 48 patients under the care of a single surgeon were randomized into two groups of 24. There were no statistically significant demographic differences at baseline. Three patients were lost to follow-up. There was a statistically significant difference in pain scores favoring the study group compared with the control group at 3 and 6 weeks postoperatively (pā€‰<ā€‰0.05), and a statistically significant difference in WOMAC scores favoring the study group compared with the control group at 3 and 6 weeks postoperatively (pā€‰=ā€‰0.01). Synovial fluid replacement with sodium hyaluronate following arthroscopic knee surgery conferred statistically significant improvements in pain and function scores compared with Bupivacaine in the short term (3-6 weeks).

PMID:
26551066
DOI:
10.1055/s-0035-1566736
[Indexed for MEDLINE]

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