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Iran J Allergy Asthma Immunol. 2015 Jun;14(3):338-40.

Familial Churg-Strauss Syndrome in a Sister and Brother.

Author information

1
Department of Allergy and Clinical Immunology, Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
2
Department of Allergy and Clinical Immunology, Shiraz University of Medical Sciences, Shiraz, Iran.

Abstract

Churg-Strauss syndrome (CSS) is a granulomatous small vessel vasculitis. It is characterized by asthma, allergic granulomatosis and vasculitis. This syndrome is rare in children. A 5 years old boy was admitted with cough, fever and dyspnea for 2 weeks. On the basis of laboratory data (peripheral eosinophilia), associated with skin biopsy, and history of CSS in his sister, this disease was eventually diagnosed. The patient had good response to corticosteroid. In every asthmatic patient with prolonged fever, eosinophilia and multisystemic involvment, CSS should be considered.

KEYWORDS:

Children; Churg-Strauss syndrome; Vasculitis

PMID:
26546904
[Indexed for MEDLINE]
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