Two new polyketides from Nocardiopsis lucentensis DSM 44048

Nat Prod Res. 2016;30(9):1036-41. doi: 10.1080/14786419.2015.1104674. Epub 2015 Nov 5.

Abstract

Two new polyketides, namely lucentides A (1) and B (2), together with 19-hydroxyprotylonolide (3) were isolated from Nocardiopsis lucentensis DSM 44048. Their structures were elucidated by analysis of their high-resolution mass spectrometry (HR-MS) and 1D, 2D nuclear magnetic resonance (NMR) spectroscopic data. The antibacterial activities of compounds 1-3 were evaluated.

Keywords: Nocardiopsis lucentensis; Polyketides; spectroscopic data.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actinomycetales / chemistry*
  • Anti-Bacterial Agents / analysis
  • Anti-Bacterial Agents / pharmacology
  • Anti-Infective Agents / analysis*
  • Anti-Infective Agents / pharmacology*
  • Antifungal Agents / analysis
  • Antifungal Agents / pharmacology
  • Fermentation
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Microbial Sensitivity Tests
  • Polyketides / analysis*
  • Polyketides / pharmacology*
  • Spectrometry, Mass, Electrospray Ionization

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antifungal Agents
  • Polyketides
  • lucentide A
  • lucentide B