Format

Send to

Choose Destination
Ann Indian Acad Neurol. 2015 Sep;18(Suppl 1):S11-5. doi: 10.4103/0972-2327.164816.

Neuromyelitis optica spectrum disorders: An update.

Author information

1
Professor of Neurology, KS Hegde Medical Academy, Nitte University, Mangalore, Karnataka, India.

Abstract

Recent advances in the understanding of neuromyelitis optica spectrum of disorders (NMOSD) have expanded. Diagnostic criteria have changed over the years. The clinical spectrum of disease manifestations are now understood to include sites outside the spinal cord and optic nerve. A variety of autoimmune diseases may coexist with this disorder. Non neurological manifestations have been recently reported. Novel biomarkers other than aquoporin 4 Immunoglobulin G (anti AQP4-IgG) have been discovered which may have clinical relevance. In particul myelin associated oligoglycoprotein antibody (MOG-Ab) associated NMOSD may be relatively benign. This update describes some of these new findings highlighting the clinical manifestations, biomarkers associated with the disease and magnetic resonance imaging characteristics of brain and spinal cord.

KEYWORDS:

Anti aquaporin 4 -IgG; MRI; NMOSD; clinical features

Supplemental Content

Full text links

Icon for Medknow Publications and Media Pvt Ltd Icon for PubMed Central
Loading ...
Support Center