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Diabetes Ther. 2015 Dec;6(4):425-468. Epub 2015 Nov 4.

Sleep Optimization and Diabetes Control: A Review of the Literature.

Author information

1
Department of Medicine, Weill Cornell Medical College in Qatar, Room C008, Qatar Foundation, Education City, PO Box 24144, Doha, Qatar.
2
Department of Medicine, Weill Cornell Medical College, New York, USA.
3
Department of Medicine, Weill Cornell Medical College in Qatar, Room C008, Qatar Foundation, Education City, PO Box 24144, Doha, Qatar. szt2004@qatar-med.cornell.edu.

Abstract

Pre-diabetes and diabetes occur secondary to a constellation of pathophysiological abnormalities that culminate in insulin resistance, which results in reduced cellular glucose uptake and increased glucose production. Although pre-diabetes and diabetes have a strong genetic basis, they are largely environmentally driven through lifestyle factors. Traditional lifestyle factors such as diet and physical activity do not fully explain the dramatic rise in the incidence and prevalence of diabetes mellitus. Sleep has emerged as an additional lifestyle behavior, important for metabolic health and energy homeostasis. In this article, we review the current evidence surrounding the sleep-diabetes association.

KEYWORDS:

Chronotype; Circadian misalignment; Obesity; Sleep duration; Sleep quality; Type 2 diabetes mellitus

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