The one-step synthesis and surface functionalization of dumbbell-like gold-iron oxide nanoparticles: a chitosan-based nanotheranostic system

Nina Kostevsek; Erica Locatelli; Chiara Garrovo; Francesca Arena; Ilaria Monaco; Ivaylo Petrov Nikolov; Saso Sturm; Kristina Zuzek Rozman; Vito Lorusso; Pierangela Giustetto; Paola Bardini; Stefania Biffi; Mauro Comes Franchini

doi:10.1039/c5cc08275g

The one-step synthesis and surface functionalization of dumbbell-like gold-iron oxide nanoparticles: a chitosan-based nanotheranostic system

Chem Commun (Camb). 2016 Jan 7;52(2):378-81. doi: 10.1039/c5cc08275g. Epub 2015 Nov 2.

Authors

Nina Kostevsek¹, Erica Locatelli, Chiara Garrovo, Francesca Arena, Ilaria Monaco, Ivaylo Petrov Nikolov, Saso Sturm, Kristina Zuzek Rozman, Vito Lorusso, Pierangela Giustetto, Paola Bardini, Stefania Biffi, Mauro Comes Franchini

Affiliation

¹ Department for Nanostructured Materials K-7, Jozef Stefan Institute, Jamova cesta 39 SI-1000, Ljubljana, Slovenia.

PMID: 26524586
DOI: 10.1039/c5cc08275g

Abstract

The first one-step synthesis of dumbbell-like gold-iron oxide nanoparticles has been reported here. Surface functionalization with a biocompatible chitosan matrix allowed us to obtain a novel targetable diagnostic and therapeutic tool.

MeSH terms

Chitosan / chemistry*
Chitosan / radiation effects
Energy Transfer
Ferrosoferric Oxide / chemistry*
Ferrosoferric Oxide / radiation effects
Gold / chemistry*
Gold / radiation effects
Light
Metal Nanoparticles / chemistry*
Metal Nanoparticles / radiation effects
Molecular Structure
Particle Size
Photoacoustic Techniques
Surface Properties
Theranostic Nanomedicine / instrumentation

Substances

Gold
Chitosan
Ferrosoferric Oxide