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Pan Afr Med J. 2015 Jul 30;21:229. doi: 10.11604/pamj.2015.21.229.7380. eCollection 2015.

Multidisciplinary approach to genomics research in Africa: the AfriCRAN model.

Author information

1
Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA. U.S.A.
2
Department of Orthodontics, University of Dundee, Scotland. UK.
3
South African National Bioinformatics Institute, University of the Western Cape, Private Bag, X17, Bellville 7535, South Africa.
4
Department of Oral and Maxillofacial Surgery, College of Medicine, University of Lagos, Lagos. Nigeria.
5
Department of surgery School of Medicine Faculty of health sciences Addis Ababa University, Addis Ababa. Ethiopia.
6
Department of Oral and Maxillofacial Surgery, Kigali Health Institute, P.O. Box 3286, Kigali, Rwanda.
7
Human Virology Laboratory, Nigerian Institute of Medical Research, 6, Edmond Crescent, P.M.B. 2013, Yaba, Lagos, Nigeria.
8
Department of Plastic Surgery, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, P.O. Box 448, KNUST, Kumasi, Ghana.
9
Department of Oral and Maxillofacial Surgery, Aminu Kano University Teaching Hospital, Kano. Nigeria.
10
Department of Oral and Maxillofacial Surgery, University of Maiduguri Teaching Hospital, Maiduguri. Nigeria.
11
Department of Oral and Maxillofacial Surgery, Obafemi Awolowo University, Ile-Ife. Nigeria.
12
Department of Biostatistics, University of Nigeria, Nssukka. Nigeria.
13
Department of Plastic Surgery, National Orthopedic hospital, Enugu. Nigeria.
14
Department of Computer and Information Sciences and Covenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
15
Department of Plastic and Reconstructive Surgery, Ladoke Akintola University Ogbomosho. Nigeria.
16
Department of Pediatrics, University of Ilorin. Nigeria.
17
Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, U.S.A.

Abstract

This article is an outcome of the African Craniofacial Anomalies Research Network (AfriCRAN) Human Hereditary and Health (H3A) grant planning meeting in 2012 in Lagos, Nigeria. It describes the strengths of a multidisciplinary team approach to solving complex genetic traits in the craniofacial region. It also highlights the different components and argues for the composition of similar teams to fast track the discovery of disease genes, diagnostic tools, improved clinical treatment and ultimately prevention of diseases.

KEYWORDS:

Africa; Genomics; Multidisciplinary team

PMID:
26523171
PMCID:
PMC4607986
DOI:
10.11604/pamj.2015.21.229.7380
[Indexed for MEDLINE]
Free PMC Article

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