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J Heart Lung Transplant. 2015 Dec;34(12):1495-504. doi: 10.1016/j.healun.2015.10.003. Epub 2015 Oct 8.

Seventh INTERMACS annual report: 15,000 patients and counting.

Author information

1
Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: jkirklin@uab.edu.
2
Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.
3
Department of Surgery, University of Michigan, Ann Arbor, Michigan.
4
Department of Surgery, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania.
5
Department of Medicine, Brigham & Women's Hospital, Boston, Massachusetts.
6
Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.
7
Division of Cardiovascular Diseases, Advanced Technologies and Surgery Branch, National Heart Lung and Blood Institute, Bethesda, Maryland.
8
Department of Medicine, Cleveland Clinic Foundation Lerner College of Medicine, Cleveland, Ohio.

Abstract

The seventh annual report of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) summarizes the first 9 years of patient enrollment. The Registry includes >15,000 patients from 158 participating hospitals. Trends in device strategy, patient profile at implant and survival are presented. Risk factors for mortality with continuous-flow pumps are updated, and the major causes/modes of death are presented. The adverse event burden is compared between eras, and health-related quality of life is reviewed. A detailed analysis of outcomes after mechanical circulatory support for ambulatory heart failure is presented. Recent summary data from PediMACS and MedaMACS is included. With the current continuous-flow devices, survival at 1 and 2 years is 80% and 70%, respectively.

KEYWORDS:

INTERMACS; advanced heart failure; destination therapy; mechanical support; ventricular assist device

PMID:
26520247
DOI:
10.1016/j.healun.2015.10.003
[Indexed for MEDLINE]
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