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Alcohol. 2015 Dec;49(8):767-72. doi: 10.1016/j.alcohol.2015.09.002. Epub 2015 Oct 8.

Summary of the 2014 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Author information

1
Alcohol Research Program, Burn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States; Integrative Cell Biology Program, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States.
2
Alcohol Research Program, Burn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States.
3
Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, United States; Department of Veterans' Affairs Research, Omaha, NE, United States.
4
Department of Medicine, Emory University, Atlanta, GA, United States.
5
Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA, United States.
6
Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY, United States.
7
Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Emory University School of Medicine, Atlanta, GA, United States.
8
Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, IA, United States.
9
Department of Medicine, University of Massachusetts School of Medicine, Worcester, MA, United States.
10
Alcohol Research Program, Burn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States; Integrative Cell Biology Program, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States; Department of Microbiology and Immunology, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States.
11
Alcohol Research Program, Burn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States; Integrative Cell Biology Program, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States; Department of Microbiology and Immunology, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States. Electronic address: mchoudhry@luc.edu.

Abstract

On November 21, 2014 the 19th annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at Loyola University Chicago Health Sciences Campus in Maywood, Illinois. The meeting focused broadly on inflammatory cell signaling responses in the context of alcohol and alcohol-use disorders, and was divided into four plenary sessions focusing on the gut and liver, lung infections, general systemic effects of alcohol, and neuro-inflammation. One common theme among many talks was the differential roles of macrophages following both chronic and acute alcohol intoxication. Macrophages were shown to play significant roles in regulating inflammation, oxidative stress, and viral infection following alcohol exposure in the liver, lungs, adipose tissue, and brain. Other work examined the role of alcohol on disease progression in a variety of pathologies including psoriasis, advanced stage lung disease, and cancer.

KEYWORDS:

Ethanol; Intestines; Liver; Lungs; Neuro-inflammation

PMID:
26520175
PMCID:
PMC4691366
DOI:
10.1016/j.alcohol.2015.09.002
[Indexed for MEDLINE]
Free PMC Article

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