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Contraception. 2016 Jan;93(1):11-6. doi: 10.1016/j.contraception.2015.10.002. Epub 2015 Oct 26.

The safety of hormonal contraceptives for women living with HIV and their sexual partners.

Author information

1
Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.
2
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
3
Division of Reproductive Health, US Centers for Disease Control and Prevention, Atlanta, GA, USA.

Abstract

BACKGROUND:

Hormonal contraceptives are important for the health and well-being of some women living with HIV, so evaluation of evidence regarding their safety vis-à-vis HIV-related risks is important.

METHODS:

We updated two prior systematic reviews on the impact of hormonal contraception (HC) on HIV disease progression and female-to-male HIV transmission.

RESULTS:

One new study finds no increased risk for HIV disease progression or death associated with oral contraceptive use [adjusted (adj) hazard ratio (HR) 0.83, confidence interval [CI] 0.48-1.44] or injectables (adj HR 0.72, CI 0.53-0.98). Three new studies did not find significantly increased risks for measures of female-to-male HIV transmission with HC use.

CONCLUSIONS:

Hormonal contraceptive methods do not appear to accelerate HIV disease progression. More research is needed to clarify whether HC impacts HIV transmissibility.

KEYWORDS:

HIV; Hormonal contraception; injectable contraceptives; oral contraceptives

[Indexed for MEDLINE]

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