Format

Send to

Choose Destination
Semin Cell Dev Biol. 2015 Sep;45:18-23. doi: 10.1016/j.semcdb.2015.09.026. Epub 2015 Oct 26.

Cell healing: Calcium, repair and regeneration.

Author information

1
Cell and Molecular Biology Graduate Program, Laboratory of Cell and Molecular Biology, 1525 Linden Drive, Madison, WI, USA.
2
Cell and Molecular Biology Graduate Program, Laboratory of Cell and Molecular Biology, 1525 Linden Drive, Madison, WI, USA; Department of Zoology, University of Wisconsin-Madison, 1525 Linden Drive, Madison, WI, USA. Electronic address: wmbement@wisc.edu.

Abstract

Cell repair is attracting increasing attention due to its conservation, its importance to health, and its utility as a model for cell signaling and cell polarization. However, some of the most fundamental questions concerning cell repair have yet to be answered. Here we consider three such questions: (1) How are wound holes stopped? (2) How is cell regeneration achieved after wounding? (3) How is calcium inrush linked to wound stoppage and cell regeneration?

KEYWORDS:

Calcium; Patching; Plasma membrane repair; Regeneration; Rho GTPase

PMID:
26514621
PMCID:
PMC4849125
DOI:
10.1016/j.semcdb.2015.09.026
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center