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Expert Rev Clin Pharmacol. 2016;9(1):27-34. doi: 10.1586/17512433.2016.1100072. Epub 2015 Oct 29.

Bupropion-SR plus naltrexone-SR for the treatment of mild-to-moderate obesity.

Author information

1
a Comprehensive Weight Control Center, Division of Endocrinology, Diabetes & Metabolism , Weill Cornell Medical College , New York , NY , USA.

Abstract

Naltrexone-bupropion is a recently approved drug combination for chronic weight management. In this article, we discuss the rationale for its use as a combination followed by a comprehensive review of safety and efficacy data from major preclinical, phase II and III clinical trials.

KEYWORDS:

Naltrexone; bupropion; obesity; type 2 diabetes; weight loss

PMID:
26512740
DOI:
10.1586/17512433.2016.1100072
[Indexed for MEDLINE]

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