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J Clin Microbiol. 2016 Jan;54(1):197-9. doi: 10.1128/JCM.02093-15. Epub 2015 Oct 28.

Are Pathogenic Leptospira Species Agents of Community-Acquired Pneumonia? Case Reports of Leptospirosis Presenting as Pneumonia.

Author information

1
Department of Internal Medicine, Faculty of Medicine Diponegoro University-Dr. Kariadi Hospital, Semarang, Central Java, Indonesia National Reference Laboratory for Leptospira, Dr. Kariadi Hospital, Semarang, Central Java, Indonesia mhgasem@yahoo.com.
2
Department of Microbiology, Faculty of Medicine Diponegoro University-Dr. Kariadi Hospital, Semarang, Central Java, Indonesia.
3
KIT Biomedical Research, WHO/FAO/OIE and National Leptospirosis Reference Center, Royal Tropical Institute, Amsterdam, North Holland, The Netherlands.
4
Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, South Holland, The Netherlands.
5
Department of Internal Medicine, Faculty of Medicine Diponegoro University-Dr. Kariadi Hospital, Semarang, Central Java, Indonesia.
6
National Reference Laboratory for Leptospira, Dr. Kariadi Hospital, Semarang, Central Java, Indonesia Department of Microbiology, Faculty of Medicine Diponegoro University-Dr. Kariadi Hospital, Semarang, Central Java, Indonesia.
7
Department of Infectious Diseases, Leiden University Medical Center, Leiden, South Holland, The Netherlands.

Abstract

We report four Indonesian cases meeting the clinical and radiological criteria for community-acquired pneumonia and other findings suggestive of leptospirosis. Quantitative PCR (qPCR) analyses of serum and urine samples and serology confirmed the diagnosis of leptospirosis in each. Results of qPCR analysis of throat swabs were concordant with those obtained with acute-phase serum samples, which suggests its potential for use as a noninvasive diagnostic tool for leptospirosis.

PMID:
26511741
PMCID:
PMC4702746
DOI:
10.1128/JCM.02093-15
[Indexed for MEDLINE]
Free PMC Article

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