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Interv Neuroradiol. 2015 Dec;21(6):742-9. doi: 10.1177/1591019915609131. Epub 2015 Oct 23.

Delayed vertebral body collapse after stereotactic radiosurgery and radiofrequency ablation: Case report with histopathologic-MRI correlation.

Author information

1
Mallinckrodt Institute of Radiology, Siteman Cancer Center, Washington University School of Medicine, Saint Louis, MO, USA wallacea@mir.wustl.edu.
2
Washington University School of Medicine, Saint Louis, MO, USA.
3
Department of Pathology and Immunology, Division of Anatomic Pathology, Washington University School of Medicine, Saint Louis, MO, USA.
4
Department of Radiation Oncology, Siteman Cancer Center, Washington University School of Medicine, Saint Louis, MO, USA.
5
Mallinckrodt Institute of Radiology, Siteman Cancer Center, Washington University School of Medicine, Saint Louis, MO, USA.

Abstract

Stereotactic radiosurgery and percutaneous radiofrequency ablation are emerging therapies for pain palliation and local control of spinal metastases. However, the post-treatment imaging findings are not well characterized and the risk of long-term complications is unknown. We present the case of a 46-year-old woman with delayed vertebral body collapse after stereotactic radiosurgery and radiofrequency ablation of a painful lumbar metastasis. Histopathologic-MRI correlation confirmed osteonecrosis as the underlying etiology and demonstrated that treatment-induced vascular fibrosis and tumor progression can have identical imaging appearances.

KEYWORDS:

Metastatic spine disease; radiofrequency ablation; spinal stereotactic radiosurgery; vertebral augmentation; vertebral compression fracture

PMID:
26500233
PMCID:
PMC4757353
DOI:
10.1177/1591019915609131
[Indexed for MEDLINE]
Free PMC Article

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