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Radiother Oncol. 2015 Oct;117(1):44-8. doi: 10.1016/j.radonc.2015.08.011.

Patient reported outcomes following stereotactic ablative radiotherapy or surgery for stage IA non-small-cell lung cancer: Results from the ROSEL multicenter randomized trial.

Author information

1
Department of Radiation Oncology, VU University Medical Center, Amsterdam, Netherlands; Department of Radiation Oncology, London Regional Cancer Program, Canada. Electronic address: dr.alexlouie@gmail.com.
2
Department of Biometrics, Netherlands Cancer Institute, Amsterdam, Netherlands.
3
Department of Radiation Oncology, London Regional Cancer Program, Canada.
4
Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, Netherlands.
5
Department of Cardiothoracic Surgery, VU University Medical Center, Amsterdam, Netherlands.
6
Department of Radiation Oncology, University Medical Center Groningen, Netherlands.
7
Department of Pulmonary Diseases, University Medical Center Groningen, Netherlands.
8
Department of Pulmonary Diseases, Catharina Hospital, Eindhoven, Netherlands.
9
Department of Radiation Oncology, Catharina Hospital, Eindhoven, Netherlands.
10
Department of Radiation Oncology, VU University Medical Center, Amsterdam, Netherlands.

Abstract

We report quality of life and indirect costs from patient reported outcomes from the ROSEL randomized control trial comparing stereotactic ablative radiotherapy (SABR, also known as stereotactic body radiotherapy or SBRT) versus surgical resection for medically operable stage IA non-small cell lung cancer. ROSEL closed prematurely after accruing and randomizing 22 patients. This exploratory analysis found the global health related quality of life and indirect costs to be significantly favorable and cheaper, with SABR.

KEYWORDS:

Lung cancer; Patient reported outcomes; Quality of life; SABR; SBRT; Surgery

PMID:
26492839
DOI:
10.1016/j.radonc.2015.08.011
[Indexed for MEDLINE]

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