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Biomed Res Int. 2015;2015:183821. doi: 10.1155/2015/183821. Epub 2015 Sep 27.

Determination of Serum Lost Goodwill Target Proteome in Patients with Severe Traumatic Brain Injury.

Author information

1
Department of Neurosurgery, Shanxi Provincial People's Hospital, Taiyuan 030001, China.
2
Department of Neurosurgery, Shanxi Provincial People's Hospital, Taiyuan 030001, China ; Department of Neurosurgery, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
3
Department of Neurosurgery, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430077, China.
4
Department of Neurosurgery, Wuhan Central Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430014, China.
5
Department of Neurosurgery, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Abstract

This study investigates the biokinetics of LGT proteome, a potential biomarker of severe TBI, in serum of severe TBI patients. The LGT proteome presents in the serum of severe TBI patients. The abundance diversity of LGT proteome is closely associated with pathologic condition of TBI patients. Serum LGT proteome may be used as a promising marker for evaluating severity of severe TBI.

PMID:
26491659
PMCID:
PMC4600481
DOI:
10.1155/2015/183821
[Indexed for MEDLINE]
Free PMC Article

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