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Nucleic Acids Res. 2016 Jan 4;44(D1):D180-3. doi: 10.1093/nar/gkv1081. Epub 2015 Oct 20.

5SRNAdb: an information resource for 5S ribosomal RNAs.

Author information

1
Department of Computational Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland mszyman@amu.edu.pl.
2
Department of Computational Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland.
3
Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznan, Poland.
4
Institute for Chemistry and Biochemistry, Free University Berlin, 14195 Berlin, Germany.
5
Department of Computational Biology, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61-614 Poznan, Poland wmk@amu.edu.pl.

Abstract

Ribosomal 5S RNA (5S rRNA) is the ubiquitous RNA component found in the large subunit of ribosomes in all known organisms. Due to its small size, abundance and evolutionary conservation 5S rRNA for many years now is used as a model molecule in studies on RNA structure, RNA-protein interactions and molecular phylogeny. 5SRNAdb (http://combio.pl/5srnadb/) is the first database that provides a high quality reference set of ribosomal 5S RNAs (5S rRNA) across three domains of life. Here, we give an overview of new developments in the database and associated web tools since 2002, including updates to database content, curation processes and user web interfaces.

PMID:
26490961
PMCID:
PMC4702797
DOI:
10.1093/nar/gkv1081
[Indexed for MEDLINE]
Free PMC Article

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