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J Asian Nat Prod Res. 2016;18(2):125-33. doi: 10.1080/10286020.2015.1090984. Epub 2015 Oct 19.

Flavonoids from Pronephrium megacuspe.

Author information

1
a College of Chemistry and Chemical Engineering , Zhongkai University of Agriculture and Engineering , Guangzhou 510225 , China.
2
b Key Laboratory of Natural Pesticides and Chemical Biology, Ministry of Education , South China Agricultural University , Guangzhou 510630 , China.
3
c State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources , South China Agricultural University , Guangzhou 510630 , China.
4
d Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden , Chinese Academy of Sciences , Guangzhou 510650 , China.

Abstract

A chemical investigation of the whole plant of Pronephrium megacuspe (Bak.) Holtt. led to the isolation of four flavonoids, pronephrones A-D (1-4), which were firstly reported. The chemical structures of four compounds were established using spectroscopic methods. These isolates were further evaluated for cytotoxicity to ovarian cells of Spodoptera litura Fabricius.

KEYWORDS:

Pronephrium megacuspe; Thelypteridaceae; cytotoxicity; pronephrones A–D

PMID:
26479429
DOI:
10.1080/10286020.2015.1090984
[Indexed for MEDLINE]

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