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Rheum Dis Clin North Am. 2015 Nov;41(4):615-22. doi: 10.1016/j.rdc.2015.07.005. Epub 2015 Aug 24.

Early Psoriatic Arthritis.

Author information

1
Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK. Electronic address: prsnjm@bath.ac.uk.

Abstract

Skin psoriasis is a major risk factor for the development of psoriatic arthritis. Recent studies have shown that delayed diagnosis is associated with long-term adverse outcomes. Screening questionnaires have revealed a potential burden of undiagnosed disease. Lifestyle factors and genetic and soluble biomarkers have come under scrutiny as risk factors. Imaging modalities may have an important role in detecting early change. With more effective treatments, it may be possible to prevent significant joint damage and associated disability. However, the precise nature of accurate and cost-effective screening strategies remains to be determined.

KEYWORDS:

Biomarkers; Genetic screening; Psoriasis; Psoriatic arthritis

PMID:
26476222
DOI:
10.1016/j.rdc.2015.07.005
[Indexed for MEDLINE]

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