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Int J Cardiol. 2016 Jan 1;202:804-9. doi: 10.1016/j.ijcard.2015.09.116. Epub 2015 Sep 30.

Medical factors that predict quality of life for young adults with congenital heart disease: What matters most?

Author information

1
Center for Biobehavioral Health, Nationwide Children's Hospital, Columbus, OH, United States; Department of Pediatrics, The Ohio State University, Columbus, OH, United States. Electronic address: jamie.jackson2@nationwidechildrens.org.
2
College of Medicine, The Ohio State University, Columbus, OH, United States.
3
Center for Biobehavioral Health, Nationwide Children's Hospital, Columbus, OH, United States.
4
Center for Biobehavioral Health, Nationwide Children's Hospital, Columbus, OH, United States; Department of Pediatrics, The Ohio State University, Columbus, OH, United States.
5
Columbus Ohio Adult Congenital Heart Disease Program, Heart Center, Nationwide Children's Hospital, Columbus, OH, United States; Departments of Internal Medicine and Pediatrics, The Ohio State University, Columbus, OH, United States.

Abstract

BACKGROUND:

Identify demographic and medical status indicators that account for variability in physical and emotional health-related quality of life (QoL) among young adults with congenital heart disease (CHD) as compared to traditional lesion severity categories.

METHODS:

Cross-sectional study of 218 young adult survivors of CHD (mean=25.7, SD=7.1 years). Participants were recruited from pediatric and adult CHD clinics at a pediatric and an adult hospital. Stepwise linear regression examined the unique contribution of demographic (age; sex; estimated income) and medical status indicators (comorbid conditions; treatment modality; ventricular function/functional capacity) on QoL compared to traditional lesion severity categories (simple; moderate; complex).

RESULTS:

Lesion severity category accounted for a small portion of the variance in physical QoL (3%), but was not associated with emotional QoL. Lesion severity did not significantly contribute to the variability in physical QoL once other variables were entered. Having an estimated income of ≤$30,000, taking more than one cardiac-related medication, and having a New York Heart Association (NYHA) functional class designation>I was associated with poorer physical QoL and explained 23% of the variability. NYHA class was the only variable that explained a unique proportion of variance (7%) in emotional QoL, and having a NYHA class designation>I was associated with greater risk for poorer emotional functioning.

CONCLUSIONS:

Findings suggested that several indicators readily available to treatment teams may provide important information about the risk for poor patient-reported outcomes of physical and emotional QoL among CHD survivors.

KEYWORDS:

Congenital heart defects; Quality of life

PMID:
26476036
PMCID:
PMC4718071
DOI:
10.1016/j.ijcard.2015.09.116
[Indexed for MEDLINE]
Free PMC Article

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