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Urol Clin North Am. 2015 Nov;42(4):537-45. doi: 10.1016/j.ucl.2015.07.003. Epub 2015 Aug 11.

Asymptomatic Bacteriuria in Noncatheterized Adults.

Author information

1
Department of Urology, University of Pittsburgh Medical Center, 300 Halket Street, Suite 4710, Pittsburgh, PA 15213, USA.
2
Department of Urology, University of Pittsburgh Medical Center, 300 Halket Street, Suite 4710, Pittsburgh, PA 15213, USA. Electronic address: taylora10@upmc.edu.

Abstract

Asymptomatic bacteriuria (ASB) is a common finding and frequently detected in premenopausal nonpregnant women, institutionalized patients, patients with diabetes mellitus, and the ambulatory elderly population. Despite clear recommendations regarding diagnosis and management of ASB in these populations from the Infectious Diseases Society of America (IDSA), there remains an alarming rate of antimicrobial overuse. This article reviews definitions of ASB, epidemiology of ASB, literature surrounding ASB in diabetic patients, risk factors of ASB, microbiologic data regarding bacterial virulence, use of ASB strains for treatment of symptomatic urinary tract infection, and approaches to addressing translational barriers to implementing IDSA recommendations regarding diagnosis and management of ASB.

KEYWORDS:

Antimicrobial overtreatment; Asymptomatic bacteriuria; IDSA; Live biotherapeutics; Translational barriers; Urinary tract infection

PMID:
26475950
DOI:
10.1016/j.ucl.2015.07.003
[Indexed for MEDLINE]

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