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Biotechnol Lett. 2016 Feb;38(2):223-33. doi: 10.1007/s10529-015-1977-z. Epub 2015 Oct 15.

Application of magnetic nanoparticles in smart enzyme immobilization.

Author information

1
Faculty of Chemical Engineering, Sahand University of Technology, Tabriz, Iran.
2
Faculty of Chemical Engineering, Sahand University of Technology, Tabriz, Iran. h_jafarizadeh@sut.ac.ir.
3
Faculty of Science and Engineering, School of Engineering, University of Waikato, Hamilton, 3240, New Zealand. aydinb@waikato.ac.nz.
4
Department of Chemical Engineering, Faculty of Engineering, Tabriz Branch, Islamic Azad University, Tabriz, Iran.

Abstract

Immobilization of enzymes enhances their properties for efficient utilization in industrial processes. Magnetic nanoparticles, due to their high surface area, large surface-to-volume ratio and easy separation under external magnetic fields, are highly valued. Significant progress has been made to develop new catalytic systems that are immobilized onto magnetic nanocarriers. This review provides an overview of recent developments in enzyme immobilization and stabilization protocols using this technology. The current applications of immobilized enzymes based on magnetic nanoparticles are summarized and future growth prospects are discussed. Recommendations are also given for areas of future research.

KEYWORDS:

Enzyme; Enzyme stabilization; Immobilization; Magnetic nanoparticle; Nanoparticles

PMID:
26472272
DOI:
10.1007/s10529-015-1977-z
[Indexed for MEDLINE]

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