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Nucleic Acids Res. 2016 Jan 4;44(D1):D786-92. doi: 10.1093/nar/gkv1046. Epub 2015 Oct 13.

FlyBase: establishing a Gene Group resource for Drosophila melanogaster.

Author information

1
Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK.
2
The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
3
Department of Biology, Indiana University, Bloomington, IN 47405, USA.
4
Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK sjm41@cam.ac.uk.

Abstract

Many publications describe sets of genes or gene products that share a common biology. For example, genome-wide studies and phylogenetic analyses identify genes related in sequence; high-throughput genetic and molecular screens reveal functionally related gene products; and advanced proteomic methods can determine the subunit composition of multi-protein complexes. It is useful for such gene collections to be presented as discrete lists within the appropriate Model Organism Database (MOD) so that researchers can readily access these data alongside other relevant information. To this end, FlyBase (flybase.org), the MOD for Drosophila melanogaster, has established a 'Gene Group' resource: high-quality sets of genes derived from the published literature and organized into individual report pages. To facilitate further analyses, Gene Group Reports also include convenient download and analysis options, together with links to equivalent gene groups at other databases. This new resource will enable researchers with diverse backgrounds and interests to easily view and analyse acknowledged D. melanogaster gene sets and compare them with those of other species.

PMID:
26467478
PMCID:
PMC4702782
DOI:
10.1093/nar/gkv1046
[Indexed for MEDLINE]
Free PMC Article

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