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Chem Commun (Camb). 2016 Jan 4;52(1):76-9. doi: 10.1039/c5cc06861d.

Nanoplasmonic ruler to measure lipid vesicle deformation.

Author information

1
School of Materials Science and Engineering and Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Avenue 639798, Singapore. njcho@ntu.edu.sg.
2
Institute of Photonics and Electronics, Academy of Science of the Czech Republic, Chaberska 57, Prague 8 18251, Czech Republic.
3
School of Materials Science and Engineering and Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Avenue 639798, Singapore. njcho@ntu.edu.sg and School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive 637459, Singapore.

Abstract

A nanoplasmonic ruler method is presented in order to measure the deformation of adsorbed, nm-scale lipid vesicles on solid supports. It is demonstrated that single adsorbed vesicles undergo greater deformation on silicon oxide over titanium oxide, offering direct experimental evidence to support membrane tension-based theoretical models of supported lipid bilayer formation.

PMID:
26466086
DOI:
10.1039/c5cc06861d
[Indexed for MEDLINE]

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