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Rev Med Inst Mex Seguro Soc. 2015;53 Suppl 2:S122-30.

[HPV genotypes prevalence in México and worldwide detected by Linear Array].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

1
Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México. lfjave@yahoo.com.

Abstract

in English, Spanish

Infection with human papillomavirus (HPV) is the main factor associated with the development of cervical cancer (CC). Knowing about the prevalence of HPVs at different stages in the development of CC is important for determining the HPV oncogenic risk, the development of screening strategies, the evaluation of prevention programs, and also for vaccine designing. This paper is a meta-analysis of HPV prevalence worldwide and in Mexico from studies using the Linear Array® HPV Genotyping Test as a diagnostic test (it is the commercial test that, up to date, identifies the largest number of HPV genotypes in a single sample) in DNA of cervical samples from women with normal cytology, with low grade squamous intraepithelial lesions (LGSIL), with high grade squamous intraepithelial lesions (HGSIL) and with CC. The most prevalent genotypes after HPV-16 and -18 in women with CC varies depending on geographic region, which supports the need to develop detection and prevention strategies according to the characteristics of the population.

KEYWORDS:

Cervical cancer; HPV; Papillomavirus

PMID:
26462507
[Indexed for MEDLINE]

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