Format

Send to

Choose Destination
Nat Neurosci. 2015 Nov;18(11):1571-3. doi: 10.1038/nn.4136. Epub 2015 Oct 12.

Neural mechanisms supporting maladaptive food choices in anorexia nervosa.

Author information

1
Psychology Department, New York University, New York, New York, USA.
2
Division of Clinical Therapeutics, New York State Psychiatric Institute, New York, New York, USA.
3
Department of Psychiatry, Columbia University Medical Center, New York, New York, USA.
4
Department of Psychology, Zuckerman Mind Brain Behavior Institute, and Kavli Institute for Brain Science, Columbia University, New York, New York, USA.

Abstract

People routinely make poor choices, despite knowledge of negative consequences. The authors found that individuals with anorexia nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activity in fronto-striatal circuits was correlated with their actual food consumption in a meal the next day.

PMID:
26457555
PMCID:
PMC4624561
DOI:
10.1038/nn.4136
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center