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Mutat Res. 1989 Feb;222(2):101-10.

Application of biochemical intake markers to passive smoking measurement and risk estimation.

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Addiction Research Unit, Institute of Psychiatry, London, U.K.


Measurement of the dose received from passive smoking complements epidemiological approaches and may provide an alternative method of estimating risk. Non-smokers absorb measurable amounts of nicotine from breathing other people's smoke, and dose-response relationships are apparent. On the basis of the limited data so far available, the dose of nicotine received by the average British non-smoker may represent about 0.5% of that of the heavy cigarette smoker, ranging up to 2% in more heavily exposed individuals. The dose of carbon monoxide appears relatively greater, as does that of tobacco-specific nitrosamines. The situation with respect to tar is unclear, but nicotine may provide a better guide than does CO.

[Indexed for MEDLINE]

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